152 Insights into the pathogenesis of HHV8-driven body cavity-based lymphoma

Burkitt's lymphoma: new insights into molecular pathogenesis.

The World Health Organisation classification reports three subcategories of Burkitt's lymphoma (BL)--endemic, non-endemic, and immunodeficiency associated--proposed to reflect the major clinical and genetic subtypes of this disease. These different types of BL have been reviewed and studied by immunohistochemistry and molecular methods. The results point out the heterogeneity of BL and suggest ...

Inclusion body myositis: new insights into pathogenesis.

PURPOSE OF REVIEW The pathogenesis of sporadic inclusion body myositis is complex and the disease has a relentless course. Recent observations regarding possible mechanisms of disease may provide targets for therapy. RECENT FINDINGS Evidence is strengthening that specific T-cell and B-cell responses are ongoing in skeletal muscle in sporadic inclusion body myositis and that cytokines and chem...

Novel insights into the molecular pathogenesis of gastric MALT lymphoma

Gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) represents a distinct class of extranodal lymphoma that evolves against a background of chronic inflammation induced by persistent infection with the bacterium Helicobacter pylori. In its early stages, MALT lymphoma is an antigen-dependent disease characterised by an indolent clinical course and in most c...

Insights Into Pathogenesis

Transcriptome Based Analysis of Hodgkin Lymphoma; Insights into the Microenvironment

TRANSCRIPTOME BASED ANALYSIS OF HODGKIN LYMPHOMA; INSIGHTS INTO THE MICROENVIRONMENT